| Titre : |
Advances in cancer research |
| Titre original : |
Foundations in cancer research |
| Type de document : |
texte imprimé |
| Auteurs : |
George F. Vande Woude, Editeur scientifique ; Georg Klein (1925-....), Editeur scientifique |
| Editeur : |
Amsterdam [Pays-Bas] : Academic Press |
| Année de publication : |
1999 |
| Collection : |
Advances in cancer research, ISSN 0065-230X num. 76 |
| Importance : |
249 p. |
| Présentation : |
ill. |
| Format : |
21 cm |
| ISBN/ISSN/EAN : |
978-0-12-006676-9 |
| Note générale : |
Index |
| Langues : |
Anglais (eng) |
| Catégories : |
Cancer ; Cancer -- Recherche ; Oncologie expérimentale
|
| Index. décimale : |
616.994 |
| Résumé : |
Volume 76 of Advances in Cancer Research continues the series' goal of publishing timely and authoritative reviews in the broad field of cancer research. Ruoslahti begins the volume with a review of fibronectin and its integrin receptors in cancer. Chapter 2 by Ganter and Lipsick discusses Myb and oncogenesis. Biscardi and colleagues present their research on c-Src, receptor tyrosine kinases, and human cancer in Chapter 3. Chapter 4 by Schulz covers epidemiology of Kaposi's sarcoma and associated herpesvirus/human herpesvirus 8. The consensus on synergism between cigarette smoke and other ... |
| Note de contenu : |
Contributors to Volume 76 -- Ch. 1. Fibronectin and Its integrin receptors in cancer / E. Ruoslahti: I. Introduction -- II. Reduced adhesiveness Is needed for detachment and migration -- III. Anchorage dependence and anoikis -- IV. Cell migration and invasion -- References -- Ch. 2. Myb and dncogenesis / B. Ganter & J.S. Lipsick: I. Introduction -- II. The Myb genes -- II. Structural and functional features of the Myb proteins -- IV. Regulation of v-Myb and c-Myb -- V. Transcriptional regulation by v-Myb and c-Myb -- VI. The Myb-chromatin connection -- References -- Ch. 3. c-Src, receptor tyrosine kinases, and human cancer / J.S. Biscardi, D.A. Tice & S.J. Parsons: I. Introduction -- II. Receptor tyrosine kinases and human cancers -- III. c-Src and c-Src family members in human cancers -- IV. Mechanisms of c-Src action -- V. Potential therapeutic applications of c-Src/HERl interactions -- References -- Ch. 4. Epidemiology of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 / T.F. Schulz: I. Introduction -- II. KSHV phylogeny and molecular epidemiology -- III. Geographic distribution -- IV. KSHV prevalence in risk groups for HIV-1 transmission -- V. Transmission of KSHV -- VI. Association of KSHV with disease -- VII. Conclusion -- References -- Ch. 5. Consensus on synergism between cigarette smoke and other environmental carcinogens in the causation of lung cancer / A.E. Reif & T. Heeren: 1. Introduction -- II. Testing the significance of a finding of synergism -- III. Carcinogenic synergism and public health -- IV. Previous findings in synergism involving cigarette smoke -- V. Multistep carcinogenesis -- VI. Varying the time frame of data collection -- VII. Conclusion -- References -- Ch. 6. Carcinogenesis and natural selection: A new perspective to the genetics and epigenetics of colorectal cancer / J. Breivik & G. Gaudernack: I. Introduction -- II. Evolution and Cancer -- III. The microsatellite instability pathway -- IV. The chromosomal Instability iathway -- V. MIN versus CIN -- VI. DNA methylation and the epigenetics of cancer -- VII. Location-related carcinogenic environments -- VIII. Conclusion and perspectives; References -- Ch. 7. Antitumor immunity at work in a melanoma patient / P.G. Coulie, H. Ikeda, J.-F. Baurain & R. Chiar: I. Introduction -- II. Melanoma patient LB33 and melanoma cell lines -- III. Autologous CTLs against MEL. A cells -- IV. Identification of antigens recognized by CTLs on MEL. A cells -- V. The MEL. B cells -- VI. A new class of antitumor CTL -- VII. Conclusions -- Reference |
Advances in cancer research = Foundations in cancer research [texte imprimé] / George F. Vande Woude, Editeur scientifique ; Georg Klein (1925-....), Editeur scientifique . - Amsterdam (Pays-Bas) : Academic Press, 1999 . - 249 p. : ill. ; 21 cm. - ( Advances in cancer research, ISSN 0065-230X; 76) . ISSN : 978-0-12-006676-9 Index Langues : Anglais ( eng)
| Catégories : |
Cancer ; Cancer -- Recherche ; Oncologie expérimentale
|
| Index. décimale : |
616.994 |
| Résumé : |
Volume 76 of Advances in Cancer Research continues the series' goal of publishing timely and authoritative reviews in the broad field of cancer research. Ruoslahti begins the volume with a review of fibronectin and its integrin receptors in cancer. Chapter 2 by Ganter and Lipsick discusses Myb and oncogenesis. Biscardi and colleagues present their research on c-Src, receptor tyrosine kinases, and human cancer in Chapter 3. Chapter 4 by Schulz covers epidemiology of Kaposi's sarcoma and associated herpesvirus/human herpesvirus 8. The consensus on synergism between cigarette smoke and other ... |
| Note de contenu : |
Contributors to Volume 76 -- Ch. 1. Fibronectin and Its integrin receptors in cancer / E. Ruoslahti: I. Introduction -- II. Reduced adhesiveness Is needed for detachment and migration -- III. Anchorage dependence and anoikis -- IV. Cell migration and invasion -- References -- Ch. 2. Myb and dncogenesis / B. Ganter & J.S. Lipsick: I. Introduction -- II. The Myb genes -- II. Structural and functional features of the Myb proteins -- IV. Regulation of v-Myb and c-Myb -- V. Transcriptional regulation by v-Myb and c-Myb -- VI. The Myb-chromatin connection -- References -- Ch. 3. c-Src, receptor tyrosine kinases, and human cancer / J.S. Biscardi, D.A. Tice & S.J. Parsons: I. Introduction -- II. Receptor tyrosine kinases and human cancers -- III. c-Src and c-Src family members in human cancers -- IV. Mechanisms of c-Src action -- V. Potential therapeutic applications of c-Src/HERl interactions -- References -- Ch. 4. Epidemiology of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 / T.F. Schulz: I. Introduction -- II. KSHV phylogeny and molecular epidemiology -- III. Geographic distribution -- IV. KSHV prevalence in risk groups for HIV-1 transmission -- V. Transmission of KSHV -- VI. Association of KSHV with disease -- VII. Conclusion -- References -- Ch. 5. Consensus on synergism between cigarette smoke and other environmental carcinogens in the causation of lung cancer / A.E. Reif & T. Heeren: 1. Introduction -- II. Testing the significance of a finding of synergism -- III. Carcinogenic synergism and public health -- IV. Previous findings in synergism involving cigarette smoke -- V. Multistep carcinogenesis -- VI. Varying the time frame of data collection -- VII. Conclusion -- References -- Ch. 6. Carcinogenesis and natural selection: A new perspective to the genetics and epigenetics of colorectal cancer / J. Breivik & G. Gaudernack: I. Introduction -- II. Evolution and Cancer -- III. The microsatellite instability pathway -- IV. The chromosomal Instability iathway -- V. MIN versus CIN -- VI. DNA methylation and the epigenetics of cancer -- VII. Location-related carcinogenic environments -- VIII. Conclusion and perspectives; References -- Ch. 7. Antitumor immunity at work in a melanoma patient / P.G. Coulie, H. Ikeda, J.-F. Baurain & R. Chiar: I. Introduction -- II. Melanoma patient LB33 and melanoma cell lines -- III. Autologous CTLs against MEL. A cells -- IV. Identification of antigens recognized by CTLs on MEL. A cells -- V. The MEL. B cells -- VI. A new class of antitumor CTL -- VII. Conclusions -- Reference |
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