| Titre : |
Lead molecules from natural products : discovery and new trends |
| Type de document : |
texte imprimé |
| Auteurs : |
Mahmud T. H. Khan, Editeur scientifique ; Ather Arjumand, Editeur scientifique |
| Editeur : |
Amsterdam [Pays-Bas] : Elsevier |
| Année de publication : |
2006 |
| Importance : |
429 p. |
| Présentation : |
ill., couv. en coul. |
| Format : |
25 cm |
| ISBN/ISSN/EAN : |
978-0-444-51619-0 |
| Note générale : |
Ref. bibliogr. Index
|
| Langues : |
Anglais (eng) |
| Mots-clés : |
Plantes médicinales Materia medica végétale Plomb, composés de Plant Preparations — Pharmacologie Pharmacognosie Phytothérapie Herbes - Emploi en thérapeutique — Pharmacologie Pharmacologie |
| Index. décimale : |
615.3 |
| Résumé : |
Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents. |
| Note de contenu : |
Reverse pharmacognosy : a new concept for accelerating natural drug discovery / Quoc-Tuan Do & Philippe Bernard -- Effects of plant extracts on gene expression profiling : from macroarrays to microarray technology / Carlo Mischiati, Alessia Sereni, Mahmud Tareq Hassan Khan, Ilaria Lampronti & Roberto Gambari -- Effects of medicinal plant extracts on molecular interactions between DNA and transcription factors / Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Giordana Feriotto, Carlo Mischiati, Monica Borgatti & Roberto Gambari -- Plants with antitumor properties : from biologically active molecules to drugs / Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Elisabetta Lambertini, Roberta Piva, Monica Borgatti & Roberto Gambari -- Herbal extracts and compounds active against herpes simplex virus / Kenneth D. Thompson -- Pharmacological modulation of cough reflex / Gabriela Nosalova, Juraj Mokry & Sona Franova -- Phytotherapy of cough / Sona Franova, Gabriela Nosalova & Juraj Mokry -- The medicinal potential of black seed (Nigella sativa) and its components / Hala Gali-Muhtasib, Nahed El-Najjar & Regine Schneider-Stock -- Cyclin-dependent kinase inhibitors from natural sources : recent advances and future prospects for cancer treatment / Hala Gali-Muhtasib -- Anticancer and medicinal properties of essential oil and extracts of East Mediterranean sage (salvia triloba) / Hala Gali-Muhtasib -- Marine organisms from Brazil as source of potential anticancer agents / Letïcia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete A. Moraes, Adaïla Marta Païo Almeida, Manoel Odorico de Moraes & Tito Monteiro da Cruz Lotufo -- Anticancer potential of Northeast Brazilian plants / Cláudia Pessoa, Letïcia Veras Costa-Lotufo, Albert Leyva, Maria Elisabete Amaral de Moraes & Manoel Odorico de Moraes -- Safety and efficacy of phytomedicines / Manoel Odorico de Moraes, Fernando António Frota Bezerra, Letïcia Veras Costa-Lotufo, Cláudia Pessoa & Maria Elisabete Amaral de Moraes -- Pharmacological and biochemical profiling of lead compounds from traditional remedies : the case of Croton cajucara / Maria Aparecida M. Maciel, Tereza Neuma C. Dantas, Janaïna Keila P. Cámara, Angelo C. Pinto, Valdir F. Veiga Jr., Carlos R. Kaiser, Nuno A. Pereira, Cristina M.T.S. Carneiro, Frederico A. Vanderlinde, António J. Lapa, Aniele R. Agner, Ilce M.S. Cólus, Juliana Echevarria-Lima, Noema F. Grynberg, Andressa Esteves-Souza, Kenia Pissinate & Aurea Echevarria -- Antihypertensive peptides from natural resources / Toshiro Matsui & Kiyoshi Matsumoto -- Xanthones as therapeutic agents : chemistry and pharmacology / Noungoue Tchamo Diderot, Ngouela Silvere & Tsamo Etienne -- Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plant extracts and plant-derived compounds / Roberto Gambari & Ilaria Lampronti -- Anticancer properties of saffron, Crocus sativus Linn / José-Antonio Fernández -- Lead compounds and drug candidates from some Turkish plants for human health / Ïlkay Orhan & Bilge Sener -- Molecular design of multifunctional anti-Salmonella agents based on natural products / Isao Kubo, Ken-ichi Fujita, Ken-ichi Nihei & Aya Kubo -- Plant growth inhibitory activities by secondary metabolites isolated from Latin American flora / Carlos L. Céspedes, Juan C. Marín, Mariana Domínguez, J. Guillermo Avila & Blanca Serrato -- Metabolomics : systematic studies of the metabolic profiling / Mahmud Tareq Hassan Khan & Arjumand Ather |
Lead molecules from natural products : discovery and new trends [texte imprimé] / Mahmud T. H. Khan, Editeur scientifique ; Ather Arjumand, Editeur scientifique . - Amsterdam (Pays-Bas) : Elsevier, 2006 . - 429 p. : ill., couv. en coul. ; 25 cm. ISBN : 978-0-444-51619-0 Ref. bibliogr. Index
Langues : Anglais ( eng)
| Mots-clés : |
Plantes médicinales Materia medica végétale Plomb, composés de Plant Preparations — Pharmacologie Pharmacognosie Phytothérapie Herbes - Emploi en thérapeutique — Pharmacologie Pharmacologie |
| Index. décimale : |
615.3 |
| Résumé : |
Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents. |
| Note de contenu : |
Reverse pharmacognosy : a new concept for accelerating natural drug discovery / Quoc-Tuan Do & Philippe Bernard -- Effects of plant extracts on gene expression profiling : from macroarrays to microarray technology / Carlo Mischiati, Alessia Sereni, Mahmud Tareq Hassan Khan, Ilaria Lampronti & Roberto Gambari -- Effects of medicinal plant extracts on molecular interactions between DNA and transcription factors / Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Giordana Feriotto, Carlo Mischiati, Monica Borgatti & Roberto Gambari -- Plants with antitumor properties : from biologically active molecules to drugs / Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Elisabetta Lambertini, Roberta Piva, Monica Borgatti & Roberto Gambari -- Herbal extracts and compounds active against herpes simplex virus / Kenneth D. Thompson -- Pharmacological modulation of cough reflex / Gabriela Nosalova, Juraj Mokry & Sona Franova -- Phytotherapy of cough / Sona Franova, Gabriela Nosalova & Juraj Mokry -- The medicinal potential of black seed (Nigella sativa) and its components / Hala Gali-Muhtasib, Nahed El-Najjar & Regine Schneider-Stock -- Cyclin-dependent kinase inhibitors from natural sources : recent advances and future prospects for cancer treatment / Hala Gali-Muhtasib -- Anticancer and medicinal properties of essential oil and extracts of East Mediterranean sage (salvia triloba) / Hala Gali-Muhtasib -- Marine organisms from Brazil as source of potential anticancer agents / Letïcia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete A. Moraes, Adaïla Marta Païo Almeida, Manoel Odorico de Moraes & Tito Monteiro da Cruz Lotufo -- Anticancer potential of Northeast Brazilian plants / Cláudia Pessoa, Letïcia Veras Costa-Lotufo, Albert Leyva, Maria Elisabete Amaral de Moraes & Manoel Odorico de Moraes -- Safety and efficacy of phytomedicines / Manoel Odorico de Moraes, Fernando António Frota Bezerra, Letïcia Veras Costa-Lotufo, Cláudia Pessoa & Maria Elisabete Amaral de Moraes -- Pharmacological and biochemical profiling of lead compounds from traditional remedies : the case of Croton cajucara / Maria Aparecida M. Maciel, Tereza Neuma C. Dantas, Janaïna Keila P. Cámara, Angelo C. Pinto, Valdir F. Veiga Jr., Carlos R. Kaiser, Nuno A. Pereira, Cristina M.T.S. Carneiro, Frederico A. Vanderlinde, António J. Lapa, Aniele R. Agner, Ilce M.S. Cólus, Juliana Echevarria-Lima, Noema F. Grynberg, Andressa Esteves-Souza, Kenia Pissinate & Aurea Echevarria -- Antihypertensive peptides from natural resources / Toshiro Matsui & Kiyoshi Matsumoto -- Xanthones as therapeutic agents : chemistry and pharmacology / Noungoue Tchamo Diderot, Ngouela Silvere & Tsamo Etienne -- Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plant extracts and plant-derived compounds / Roberto Gambari & Ilaria Lampronti -- Anticancer properties of saffron, Crocus sativus Linn / José-Antonio Fernández -- Lead compounds and drug candidates from some Turkish plants for human health / Ïlkay Orhan & Bilge Sener -- Molecular design of multifunctional anti-Salmonella agents based on natural products / Isao Kubo, Ken-ichi Fujita, Ken-ichi Nihei & Aya Kubo -- Plant growth inhibitory activities by secondary metabolites isolated from Latin American flora / Carlos L. Céspedes, Juan C. Marín, Mariana Domínguez, J. Guillermo Avila & Blanca Serrato -- Metabolomics : systematic studies of the metabolic profiling / Mahmud Tareq Hassan Khan & Arjumand Ather |
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